Structure and Cooperativity in Substrate-Enzyme Interactions: Perspectives on Enzyme Engineering and Inhibitor Design.
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DOI: 10.1021/acschembio.1c00500
Abstract: Enzyme-based synthetic chemistry provides a green way to synthesize industrially important chemical scaffolds and provides incomparable substrate specificity and unmatched stereo-, regio-, and chemoselective product formation. However, using biocatalysts at an industrial scale has its… read more here.
Keywords: cooperativity; substrate enzyme; structure; protein engineering ... See more keywords