Challenges with the precise prediction of ABC-transporter interactions for improved drug discovery
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Drug Discovery"
DOI: 10.1080/17460441.2018.1493454
Abstract: ABSTRACT Introduction: Given that membrane efflux transporters can influence a drug’s pharmacokinetics, efficacy and safety, identifying potential substrates and inhibitors of these transporters is a critical element in the drug discovery and development process. Additionally,… read more here.
Keywords: drug; substrate inhibitor; efflux transporters; drug discovery ... See more keywords