The Effect of 2-Ketobutyrate on Mitochondrial Substrate-Level Phosphorylation
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemical Research"
DOI: 10.1007/s11064-019-02759-8
Abstract: The reaction catalyzed by succinate-CoA ligase in the mitochondrial matrix yields a high-energy phosphate when operating towards hydrolysis of the thioester bond of succinyl-CoA, known as mitochondrial substrate-level phosphorylation (mSLP). The catabolism of several metabolites… read more here.
Keywords: ketobutyrate; succinyl coa; substrate level; coa ... See more keywords
Promiscuous enzymes cooperate at the substrate level en route to lactazole A.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c05541
Abstract: Enzymes involved in biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs) often have relaxed specificity profiles and are able to modify diverse substrates. When several such enzymes act together during precursor peptide maturation, a… read more here.
Keywords: biosynthesis; formation; level; promiscuous enzymes ... See more keywords