Impact of curcumin on the pharmacokinetics of rosuvastatin in rats and dogs based on the conjugated metabolites
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DOI: 10.1080/00498254.2016.1183060
Abstract: Abstract 1. Plasma concentrations of curcumin-O-glucuronide (COG) and curcumin-O-sulfate (COS) significantly increased after Sprague-Dawley rats dealt with the Oatp inhibitor rifampicin, with the Cmax ascending 2.9 and 6.7 times, and the AUC0–∞ ascending 4.4 and… read more here.
Keywords: cog; inhibitor; substrate oatp1b1; significantly increased ... See more keywords