Dynamics of Substrate Processing by PPIP5K2, a Versatile Catalytic Machine.
Sign Up to like & getrecommendations! Published in 2019 at "Structure"
DOI: 10.1016/j.str.2019.03.007
Abstract: Processing of substrates by enzymes can only be fully understood through their conformational dynamics; this is particularly true for the diphosphoinositol pentakisphosphate kinase PPIP5K2, an enzyme with critical roles in cell signaling and bioenergetic homeostasis.… read more here.
Keywords: ppip5k2; processing ppip5k2; versatile catalytic; dynamics substrate ... See more keywords
Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding
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DOI: 10.1126/science.aax1033
Abstract: Protein unfolding, one substrate at a time Ubiquitin marks proteins for degradation by the proteasome. However, many substrates cannot be directly degraded because they are well folded or are located in cell membranes or in… read more here.
Keywords: substrate processing; cdc48 atpase; substrate; atpase ... See more keywords