Substrate selection by the proteasome through initiation regions
Sign Up to like & getrecommendations! Published in 2019 at "Protein Science"
DOI: 10.1002/pro.3642
Abstract: Proteins in the cell have to be eliminated once their function is no longer desired or they become damaged. Most regulated protein degradation is achieved by a large enzymatic complex called the proteasome. Many proteasome… read more here.
Keywords: degradation; substrate selection; initiation; selection proteasome ... See more keywords
Importance of aspartic acid side chain carboxylate‐arginine interaction in substrate selection of arginine 2,3‐aminomutase BlsG
Sign Up to like & getrecommendations! Published in 2023 at "Protein Science"
DOI: 10.1002/pro.4584
Abstract: The fungicide nucleoside blasticidin S features a β‐arginine, a moiety seldom revealed in the structure of natural products. BlsG, a radical SAM arginine‐2,3‐aminomutase from the blasticidin S biosynthetic pathway, displayed promiscuous activity to three basic… read more here.
Keywords: aminomutase; arginine aminomutase; blsg; substrate selection ... See more keywords
Influent salinity affects substrate selection in surface flow constructed wetlands
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-021-15036-5
Abstract: To identify the effect of influent salinity on substrate selection, a study was conducted in pilot-scale surface flow constructed wetlands (SFCWs). Compared with gravel and sand SFCWs, soil SFCWs performed similarly or worse at low… read more here.
Keywords: salinity; substrate selection; influent salinity; sfcws ... See more keywords
Aspartate residues far from the active site drive O-GlcNAc transferase substrate selection.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b06061
Abstract: O-GlcNAc is an abundant post-translational modification found on nuclear and cytoplasmic proteins in all metazoans. This modification regulates a wide variety of cellular processes, and elevated O-GlcNAc levels have been implicated in cancer progression. A… read more here.
Keywords: glcnac; aspartate residues; substrate selection; glcnac transferase ... See more keywords
Cryo-EM structure of acylpeptide hydrolase reveals substrate selection by multimerization and a multi-state serine-protease triad
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc02276a
Abstract: The first structure of tetrameric mammalian acylaminoacyl peptidase, an enzyme that functions as an upstream regulator of the proteasome through the removal of terminal N-acetylated residues from its protein substrates, was determined by cryo-EM and… read more here.
Keywords: serine protease; substrate selection; structure; cryo ... See more keywords
The substrate selection and spawning behaviour of pikeperch Sander lucioperca L. broodstock under pond conditions
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DOI: 10.1111/are.13819
Abstract: Spawning substrate is a critical factor in reproduction of commercially valuable percids. Substrate preferences of pikeperch Sander lucioperca were investigated using three types of artificial spawning substrates: long fibred brush, artificial turf and smooth plastic.… read more here.
Keywords: sander lucioperca; pikeperch sander; substrate selection; pikeperch ... See more keywords
Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies
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DOI: 10.1371/journal.pone.0195048
Abstract: Human apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3 (A3) proteins are a family of cytidine deaminases that catalyze the conversion of deoxycytidine (dC) to deoxyuridine (dU) in single-stranded DNA (ssDNA). A3 proteins act in the innate… read more here.
Keywords: substrate selection; ssdna; dna substrate; dna ... See more keywords