Probing Substrate Sequestration in Carrier Proteins using Vibrational Spectroscopy Labels
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DOI: 10.1016/j.bpj.2016.11.1860
Abstract: Carrier proteins are considered “lynchpin” enzymes of biosynthetic pathways. The E. coli acyl carrier protein (ACP) is composed of multiple alpha helices that form a hydrophobic, solvent-protected pocket that sometimes provides a cavernous hiding spot… read more here.
Keywords: sequestration; probing substrate; spectroscopy; carrier proteins ... See more keywords