Three glycoside hydrolase family 12 enzymes display diversity in substrate specificities and synergistic action between each other
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology Reports"
DOI: 10.1007/s11033-019-04999-x
Abstract: PoCel12A, PoCel12B, and PoCel12C are genes that encode glycoside hydrolase family 12 (GH12) enzymes in Penicillium oxalicum. PoCel12A and PoCel12B are typical GH12 enzymes that belong to fungal subfamilies 12-1 and 12-2, respectively. PoCel12C contains… read more here.
Keywords: diversity substrate; glycoside hydrolase; hydrolase family; family ... See more keywords
Substrate Specificities of GH8, GH39, and GH52 β-xylosidases from Bacillus halodurans C-125 Toward Substituted Xylooligosaccharides
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DOI: 10.1007/s12010-020-03451-2
Abstract: Substrate specificities of glycoside hydrolase families 8 (Rex), 39 ( Bh Xyl39), and 52 ( Bh Xyl52) β-xylosidases from Bacillus halodurans C-125 were investigated. Bh Xyl39 hydrolyzed xylotriose most efficiently among the linear xylooligosaccharides. The… read more here.
Keywords: xyl; bacillus halodurans; substrate specificities; meglca xyl ... See more keywords
CUPRA-ZYME: An assay for measuring carbohydrate-active enzyme activities, pathways and substrate specificities.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b05007
Abstract: Carbohydrate-Active enZymes (CAZymes) are involved in the synthesis, degradation and modification of carbohydrates. They play critical roles in diverse physiological and pathophysiological processes, have important industrial and biotechnological applications, are important drug targets and represent… read more here.
Keywords: pathways substrate; cupra zyme; substrate specificities; assay measuring ... See more keywords
Different substrate specificities of the two ADPR binding sites in TRPM2 channels of Nematostella vectensis and the role of IDPR
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41531-4
Abstract: NvTRPM2 (Nematostella vectensis Transient Receptor Potential Melastatin 2), the species variant of the human apoptosis-related cation channel hTRPM2, is gated by ADP-ribose (ADPR) independently of the C-terminal NUDT9H domain that mediates ADPR-directed gating in hTRPM2.… read more here.
Keywords: different substrate; adpr binding; site; substrate specificities ... See more keywords
Influence of saccharide modifications on heparin lyase III substrate specificities.
Sign Up to like & getrecommendations! Published in 2021 at "Glycobiology"
DOI: 10.1093/glycob/cwab023
Abstract: A library of 23 synthetic heparan sulfate (HS) oligosaccharides, varying in chain length, types and positions of modifications, was used to analyze the substrate specificities of heparin lyase III enzymes from both Flavobacterium heparinum and… read more here.
Keywords: iii; heparin lyase; lyase iii; sulfation ... See more keywords
Erratum for Leus et al., “Substrate Specificities and Efflux Efficiencies of RND Efflux Pumps of Acinetobacter baumannii”
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bacteriology"
DOI: 10.1128/jb.00088-20
Abstract: Volume 200, no. 13, e00049-18, 2018, [https://doi.org/10.1128/JB.00049-18][1]. Page 7, Table 2, lines 4–2 from bottom, AbΔ3 columns: For CF, “0.01” and “0.01” should read “8–16” and “Not determined,” respectively; for TRI, “0.78–1.56” and “0.78” should… read more here.
Keywords: efflux efficiencies; efficiencies rnd; substrate specificities; specificities efflux ... See more keywords
Overlapping and unique substrate specificities of ST3GAL1 and 2 during hematopoietic and megakaryocytic differentiation
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022007001
Abstract: Key Points ST3GAL1 and ST3GAL2 have both overlapping and unique substrate specificities in O-glycan sialylation during megakaryopoiesis. O-glycan sialylation is dispensable for MK production but indispensable for MK proplatelet formation. read more here.
Keywords: specificities st3gal1; unique substrate; overlapping unique; st3gal1 hematopoietic ... See more keywords