Cooperative Ionic Coordination Governs Dopamine Transporter Dynamics and Substrate Translocation: Mechanistic Insights from Molecular Simulations.
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DOI: 10.1021/acs.jcim.5c02156
Abstract: The dopamine transporter (DAT) plays a vital role in maintaining dopamine (DA) homeostasis by mediating the reuptake of DA from the synaptic cleft into presynaptic neurons, a process tightly coupled to the cotransport of two… read more here.
Keywords: transporter dynamics; mechanistic insights; substrate translocation; dynamics substrate ... See more keywords