Articles with "substrates drug" as a keyword



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Study of Endogen Substrates, Drug Substrates and Inhibitors Binding Conformations on MRP4 and Its Variants by Molecular Docking and Molecular Dynamics

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Published in 2021 at "Molecules"

DOI: 10.3390/molecules26041051

Abstract: Multidrug resistance protein-4 (MRP4) belongs to the ABC transporter superfamily and promotes the transport of xenobiotics including drugs. A non-synonymous single nucleotide polymorphisms (nsSNPs) in the ABCC4 gene can promote changes in the structure and… read more here.

Keywords: substrates drug; substrates inhibitors; drug substrates; endogen substrates ... See more keywords