Human mitochondrial amidoxime reducing component (mARC): An electrochemical method for identifying new substrates and inhibitors
Sign Up to like & getrecommendations! Published in 2017 at "Electrochemistry Communications"
DOI: 10.1016/j.elecom.2017.10.003
Abstract: Abstract As recently as 2006 the mitochondrial amidoxime reducing component (mARC) was identified as the fourth and last Mo enzyme present in humans. Its physiological role remains unknown. mARC is capable of reducing a variety… read more here.
Keywords: mitochondrial amidoxime; substrates inhibitors; amidoxime reducing; reducing component ... See more keywords
The MEROPS database of proteolytic enzymes, their substrates and inhibitors in 2017 and a comparison with peptidases in the PANTHER database
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx1134
Abstract: Abstract The MEROPS database (http://www.ebi.ac.uk/merops/) is an integrated source of information about peptidases, their substrates and inhibitors. The hierarchical classification is: protein-species, family, clan, with an identifier at each level. The MEROPS website moved to… read more here.
Keywords: enzymes substrates; substrates inhibitors; merops database; database proteolytic ... See more keywords
Study of Endogen Substrates, Drug Substrates and Inhibitors Binding Conformations on MRP4 and Its Variants by Molecular Docking and Molecular Dynamics
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DOI: 10.3390/molecules26041051
Abstract: Multidrug resistance protein-4 (MRP4) belongs to the ABC transporter superfamily and promotes the transport of xenobiotics including drugs. A non-synonymous single nucleotide polymorphisms (nsSNPs) in the ABCC4 gene can promote changes in the structure and… read more here.
Keywords: substrates drug; substrates inhibitors; drug substrates; endogen substrates ... See more keywords