Establishment and Validation of Competitive Counterflow as a Method To Detect Substrates of the Organic Anion Transporting Polypeptide 2B1.
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DOI: 10.1021/acs.molpharmaceut.8b00631
Abstract: The organic anion transporting polypeptide (OATP) 2B1 is ubiquitously expressed and known to facilitate cellular entry. It is widely accepted that transport proteins play a pivotal role in pharmacokinetics. Consequently, testing for interaction with drug… read more here.
Keywords: competitive counterflow; anion transporting; substrates oatp2b1; transporting polypeptide ... See more keywords