Structure‐Based Design of Fluorogenic Substrates Selective for Human Proteasome Subunits
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DOI: 10.1002/cbic.202000375
Abstract: Proteasomes are established therapeutic targets for hematological cancers and promising targets for autoimmune diseases. In the past, we have designed and synthesized mechanism‐based proteasome inhibitors that are selective for the individual catalytic activities of human… read more here.
Keywords: design fluorogenic; proteasome; structure based; based design ... See more keywords