Articles with "substructure based" as a keyword



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A substructure-based screening approach to uncover N-nitrosamines in drug substances

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Published in 2022 at "Journal of Food and Drug Analysis"

DOI: 10.38212/2224-6614.3400

Abstract: Drug substances are at risk of contamination with N-nitrosamines (NAs), well-known carcinogenic agents, during synthesis processes and/or long-term storage. Therefore, in this study, we developed an efficient data-based screening approach to systemically assess marketed products… read more here.

Keywords: drug substances; screening approach; based screening; substructure based ... See more keywords