Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study
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DOI: 10.1007/s11357-021-00347-9
Abstract: Ageing leaves characteristic traces in the DNA methylation make-up of the genome. However, the importance of DNA methylation in ageing remains unclear. The study of subtelomeric regions could give promising insights into this issue. Previously… read more here.
Keywords: methylation; age; subtelomeric dna; dna methylation ... See more keywords
The Alteration of Subtelomeric DNA Methylation in Aging-Related Diseases
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DOI: 10.3389/fgene.2018.00697
Abstract: The telomere is located at the end of the chromosome and consists of a non-coding, repetitive DNA sequence. As the cell divides, the length of telomere gradually decreases. A very short telomere can terminate mitosis,… read more here.
Keywords: methylation; methylation aging; dna; subtelomeric dna ... See more keywords