Analyses of extracellular protein production in Bacillus subtilis – I: Genome-scale metabolic model reconstruction based on updated gene-enzyme-reaction data
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2017.07.005
Abstract: Bacillus subtilis genome-scale model (GEM) reconstruction was stimulated by the recent sequencing and consequent re-annotations. The updated gene-enzyme-reaction data were collected from databases to reconstruct B. subtilis reaction network BsRN-2016 containing 1144 genes linked to… read more here.
Keywords: reconstruction; model; reaction; subtilis genome ... See more keywords
Greedy reduction of Bacillus subtilis genome yields emergent phenotypes of high resistance to a DNA damaging agent and low evolvability
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkad145
Abstract: Abstract Genome-scale engineering enables rational removal of dispensable genes in chassis genomes. Deviating from this approach, we applied greedy accumulation of deletions of large dispensable regions in the Bacillus subtilis genome, yielding a library of… read more here.
Keywords: evolvability; subtilis genome; bacillus subtilis; high resistance ... See more keywords