Autoinduction AND Gate Inhibits Cell Lysis to Enhance Protein Production in Bacillus subtilis Controlled by Population Density and Cell Physiological State.
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DOI: 10.1021/acssynbio.2c00624
Abstract: The extracellular protease-deficient strain Bacillus subtilis WB600 is commonly used as a chassis cell for the production of industrial proteins. However, B. subtilis WB600 exhibits an increased susceptibility to cell lysis and a reduction in biomass.… read more here.
Keywords: cell; cell lysis; subtilis wb600; production ... See more keywords