Subtle sequence variations alter tripartite complex kinetics and G-quadruplex dynamics in RNA aptamer Broccoli.
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DOI: 10.1039/c9cc09375c
Abstract: Though extensively utilized, the fluorescent RNA aptamer Broccoli is poorly characterized with an unknown structure. Spectroscopic and kinetic investigations of tripartite complex formation reveal surprising differences between Broccoli and Spinach aptamers despite extreme sequence conservation.… read more here.
Keywords: subtle sequence; sequence variations; rna aptamer; tripartite complex ... See more keywords