Adverse cardiac effects of exogenous angiotensin 1-7 in rats with subtotal nephrectomy are prevented by ACE inhibition
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DOI: 10.1371/journal.pone.0171975
Abstract: We previously reported that exogenous angiotensin (Ang) 1–7 has adverse cardiac effects in experimental kidney failure due to its action to increase cardiac angiotensin converting enzyme (ACE) activity. This study investigated if the addition of… read more here.
Keywords: adverse cardiac; cardiac effects; exogenous angiotensin; subtotal nephrectomy ... See more keywords
Factor Xa inhibitor, edoxaban ameliorates renal injury after subtotal nephrectomy by reducing epithelial‐mesenchymal transition and inflammatory response
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DOI: 10.14814/phy2.15218
Abstract: Chronic kidney disease (CKD) is an increasing and life‐threatening disease worldwide. Recent evidence indicates that blood coagulation factors promote renal dysfunction in CKD patients. Activated factor X (FXa) inhibitors are safe and first‐line drugs for… read more here.
Keywords: renal injury; edoxaban treatment; mesenchymal transition; epithelial mesenchymal ... See more keywords
EFFECT OF SIMVASTATIN ON HISTOPATHOLOGY OF THE HEART AFTER 5/6 SUBTOTAL NEPHRECTOMY
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DOI: 10.22159/ijap.2019.v11s5.t0105
Abstract: Objective: This study aims to assess the condition of cardiac histopathology through hematoxylin-eosin staining in 5/6 subtotal nephrectomyconditions.Methods: Fifteen male Swiss mice aged 3–5 months will be grouped into 3 treatment groups, namely the nephrectomy… read more here.
Keywords: heart; simvastatin; histopathology; heart muscle ... See more keywords