Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype
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DOI: 10.1038/s41467-018-04179-8
Abstract: Gastric cancer is a heterogeneous cancer, making treatment responses difficult to predict. Here we show that we identify two distinct molecular subtypes, mesenchymal phenotype (MP) and epithelial phenotype (EP), by analyzing genomic and proteomic data.… read more here.
Keywords: subtype associated; mesenchymal phenotype; gastric cancer; subtype tumors ... See more keywords
Therapeutic Implications for Intrinsic Phenotype Classification of Metastatic Castration-Resistant Prostate Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-21-4289
Abstract: Abstract Purpose: To determine whether metastatic castration–resistant prostate cancers (mCRPC) partition into molecular phenotypes corresponding to intrinsic differentiation states and ascertain whether these subtypes exhibit specific druggable features and associate with treatment outcomes. Experimental Design:… read more here.
Keywords: subtype tumors; classification; resistant prostate; castration resistant ... See more keywords