Multiple Mutations in the β1 Subunit of the Nicotinic Acetylcholine Receptor Confer Resistance to Neonicotinoids.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c01017
Abstract: The evolution of resistance to neonicotinoid insecticides threatens global agriculture. To elucidate its molecular basis, we employed Drosophila melanogaster as a model system to investigate resistance-associated mutations in the β1 subunit of nicotinic acetylcholine receptors… read more here.
Keywords: subunit nicotinic; resistance; mutations subunit; nicotinic acetylcholine ... See more keywords
Pathogenesis and pathophysiology of autosomal dominant sleep‐related hypermotor epilepsy with S284L‐mutant α4 subunit of nicotinic ACh receptor
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DOI: 10.1111/bph.14974
Abstract: The mechanisms causing spontaneous epileptic seizures, including carbamazepine‐resistant/zonisamide ‐sensitive seizures and comorbidity in autosomal dominant sleep‐related hypermotor epilepsy (ADSHE) are unclear. This study investigated functional abnormalities in thalamocortical transmission in transgenic rats bearing rat S286L‐mutant… read more here.
Keywords: subunit nicotinic; hypermotor epilepsy; sleep related; related hypermotor ... See more keywords