Development of multi-epitope driven subunit vaccine against Fasciola gigantica using immunoinformatics approach.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.07.024
Abstract: Fascioliasis, a serious helminth disease of the livestock population, results from infection with the parasite Fasciola. Despite the alarming increase in drug resistance, a safe and fully effective vaccine for fascioliasis is still not available.… read more here.
Keywords: fasciola; gigantica; subunit vaccine; vaccine ... See more keywords
Immunoinformatics approach for a novel multi-epitope subunit vaccine design against various subtypes of Influenza A virus.
Sign Up to like & getrecommendations! Published in 2021 at "Immunobiology"
DOI: 10.1016/j.imbio.2021.152053
Abstract: Vaccination is the best strategy for the control and prevention of contagious diseases caused by Influenza A viruses. Extraordinary genetic variability and continual evolvability are responsible for the virus having survival and adaptation to host… read more here.
Keywords: vaccine design; subunit vaccine; immunoinformatics approach; influenza virus ... See more keywords
Engineering a novel subunit vaccine against SARS-CoV-2 by exploring immunoinformatics approach
Sign Up to like & getrecommendations! Published in 2020 at "Informatics in Medicine Unlocked"
DOI: 10.1016/j.imu.2020.100478
Abstract: As the number of infections and deaths caused by the recent COVID-19 pandemic is increasing dramatically day-by-day, scientists are rushing towards developing possible countermeasures to fight the deadly virus, SARS-CoV-2. Although many efforts have already… read more here.
Keywords: engineering novel; subunit vaccine; novel subunit; sars cov ... See more keywords
Elaboration of tetravalent antibody responses against dengue viruses using a subunit vaccine comprised of a single consensus dengue envelope sequence.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.09.063
Abstract: Dengue viruses (DENVs) are re-emerging pathogens transmitted by mosquitoes mainly in tropical and subtropical regions. Each year, they are estimated to infect 390 million people globally. The major challenge confronting dengue vaccine development is the… read more here.
Keywords: tetravalent; consensus; subunit vaccine; vaccine ... See more keywords
Development of multi-epitope driven subunit vaccine in secretory and membrane protein of Plasmodium falciparum to convey protection against malaria infection.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.05.082
Abstract: Malaria infection is the severe health concern for a long time. As per the WHO reports, the malarial infection causes huge mortality all around the world and is incomparable with any other infectious diseases. The… read more here.
Keywords: subunit vaccine; malaria infection; vaccine; epitope ... See more keywords
Evaluation of the immune response afforded by a subunit vaccine candidate against bluetongue virus in mice and sheep.
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2018.04.007
Abstract: Bluetongue virus (BTV), a vector-borne pathogen, is the causative agent of bluetongue disease in ruminants. In view of the recent emergence of BTV in regions previously known to be free from the disease and/or specific… read more here.
Keywords: bluetongue; response; vaccine candidate; subunit vaccine ... See more keywords
Polymersomes as Stable Nanocarriers for a Highly Immunogenic and Durable SARS-CoV-2 Spike Protein Subunit Vaccine
Sign Up to like & getrecommendations! Published in 2021 at "ACS Nano"
DOI: 10.1021/acsnano.1c01243
Abstract: Multiple successful vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are urgently needed to address the ongoing coronavirus disease 2019 (Covid-19) pandemic. In the present work, we describe a subunit vaccine based on the… read more here.
Keywords: vaccine; subunit vaccine; cov spike; spike protein ... See more keywords
Subunit vaccine H56/CAF01 induces a population of circulating CD4 T cells that traffic into the Mycobacterium tuberculosis-infected lung
Sign Up to like & getrecommendations! Published in 2017 at "Mucosal immunology"
DOI: 10.1038/mi.2016.70
Abstract: The capacity of CD4 T cells to protect against Mycobacterium tuberculosis (Mtb) is governed by their ability to localize to the lung site of infection. Subunit vaccine H56/CAF01, a liposome-adjuvanted fusion protein of Mtb antigens… read more here.
Keywords: cd4 cells; subunit vaccine; h56 caf01; mycobacterium tuberculosis ... See more keywords
Development of multi-epitope subunit vaccine for protection against the norovirus’ infections based on computational vaccinology
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2020.1845799
Abstract: Abstract Human Norovirus belongs to a family Calciviridae, and was identified in the outbreak of gastroenteritis in Norwalk, due to its seasonal prevalence known as “winter vomiting disease.” Treatment of Norovirus infection is still mysterious… read more here.
Keywords: multi epitope; vaccine developed; development multi; subunit vaccine ... See more keywords
Acinetobacter baumannii subunit vaccines: recent progress and challenges.
Sign Up to like & getrecommendations! Published in 2023 at "Critical reviews in microbiology"
DOI: 10.1080/1040841x.2023.2215303
Abstract: Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes nosocomial infection with a high mortality rate in immunocompromised individuals. With the frequent emergence of multidrug-resistant A. baumannii strains that have rapidly gained resistance to most… read more here.
Keywords: subunit vaccine; baumannii subunit; acinetobacter baumannii; vaccine ... See more keywords
A combined subunit vaccine comprising of BP26, Omp25 and L7/L12 against brucellosis.
Sign Up to like & getrecommendations! Published in 2020 at "Pathogens and disease"
DOI: 10.1093/femspd/ftaa002
Abstract: The current vaccines against brucellosis namely Brucella abortus strain 19 and RB51, prevent infection in animals but pose potential risks like virulence and attenuation reversal. In this milieu, although subunit vaccination using a single potent… read more here.
Keywords: combined subunit; omp25 l12; subunit vaccine; abortus ... See more keywords