Copper(I)-catalyzed benzylic C(sp3)–H geminal difunctionalization: Successive oxidative intramolecular amidation and hydroxylation
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DOI: 10.1016/j.tet.2018.11.023
Abstract: Abstract A selective copper(I)-catalyzed benzylic C(sp3)–H geminal difunctionalization reaction of a benzylic-type sp3 carbon was developed. This novel strategy allowed simultaneous introduction of amide and hydroxyl group in a highly selective and efficient way via… read more here.
Keywords: geminal difunctionalization; catalyzed benzylic; successive oxidative; sp3 geminal ... See more keywords