Succinate Can Shuttle Reducing Power from the Hypoxic Retina to the O2-Rich Pigment Epithelium.
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DOI: 10.1016/j.celrep.2020.107606
Abstract: When O2 is plentiful, the mitochondrial electron transport chain uses it as a terminal electron acceptor. However, the mammalian retina thrives in a hypoxic niche in the eye. We find that mitochondria in retinas adapt… read more here.
Keywords: retina; succinate; succinate shuttle; pigment epithelium ... See more keywords