Chronic Watery Diarrhea in a Toddler: Think Beyond Toddler’s Diarrhea
Sign Up to like & getrecommendations! Published in 2021 at "Indian Journal of Pediatrics"
DOI: 10.1007/s12098-021-03735-3
Abstract: To the Editor: An 18-mo-old toddler, born to 2-consanguineous parents was referred for passing large volume, watery, yellow stools, 10 times/d associated with abdominal distension and poor weight gain since 7 mo of age. He… read more here.
Keywords: sucrase isomaltase; watery; gene; diarrhea ... See more keywords
Reduced efficacy of low FODMAPs diet in patients with IBS-D carrying sucrase-isomaltase (SI) hypomorphic variants
Sign Up to like & getrecommendations! Published in 2019 at "Gut"
DOI: 10.1136/gutjnl-2018-318036
Abstract: Recently in Gut and elsewhere,1–3 rare and common hypomorphic sucrase-isomaltase ( SI ) gene variants have been linked to an increased risk of IBS. Similar to congenital SI deficiency (a form of carbohydrate malabsorption caused… read more here.
Keywords: reduced efficacy; sucrase isomaltase; patients ibs; efficacy low ... See more keywords
Interaction between the α-glucosidases, sucrase-isomaltase and maltase-glucoamylase, in human intestinal brush border membranes and its potential impact on disaccharide digestion
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1160860
Abstract: The two major intestinal α-glycosidases, sucrase-isomaltase (SI) and maltase-glucoamylase (MGAM), are active towards α-1,4 glycosidic linkages that prevail in starch. These enzymes share striking structural similarities and follow similar biosynthetic pathways. It has been hypothesized… read more here.
Keywords: interaction; sucrase isomaltase; intestinal brush; maltase glucoamylase ... See more keywords