Identification of a Novel Homozygous Multi-Exon Duplication in RYR2 Among Children With Exertion-Related Unexplained Sudden Deaths in the Amish Community.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2019.5400
Abstract: Importance The exome molecular autopsy may elucidate a pathogenic substrate for sudden unexplained death. Objective To investigate the underlying cause of multiple sudden deaths in young individuals and sudden cardiac arrests that occurred in 2… read more here.
Keywords: duplication; ryr2; sudden cardiac; sudden deaths ... See more keywords
Genetic Variants Associated With Unexplained Sudden Cardiac Death in Adult White and African American Individuals.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2021.1573
Abstract: Importance Unexplained sudden cardiac death (SCD) describes SCD with no cause identified. Genetic testing helps to diagnose inherited cardiac diseases in unexplained SCD; however, the associations between pathogenic or likely pathogenic (P/LP) variants of inherited… read more here.
Keywords: unexplained sudden; death; genetic variants; sudden cardiac ... See more keywords
Risk stratification of cardiac arrhythmias and sudden cardiac death in type 2 diabetes mellitus patients receiving insulin therapy: A population-based cohort study.
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DOI: 10.1002/clc.23728
Abstract: INTRODUCTION Metabolic abnormalities may exacerbate the risk of adverse outcomes in patients with type 2 diabetes mellitus. The present study aims to assess the predictive value of HbA1c and lipid variability on the risks of… read more here.
Keywords: sudden cardiac; study; variability; hba1c ... See more keywords
The relationship between the body mass index and in-hospital mortality in patients admitted for sudden cardiac death in the United States.
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DOI: 10.1002/clc.23730
Abstract: While obesity has been shown to be associated with elevated risk for Sudden Cardiac Death (SCD), studies examining its effect on outcomes in SCD victims have shown conflicting results. We aimed to describe the body… read more here.
Keywords: hospital mortality; sudden cardiac; mortality; cardiac death ... See more keywords
Sudden cardiac death after acute decompensation in heart failure patients: implications of discharge haemoglobin levels
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DOI: 10.1002/ehf2.13414
Abstract: Heart failure (HF) patients have a high risk of mortality due to sudden cardiac death (SCD) and non‐SCD, including pump failure death (PFD). Anaemia predicts more severe symptomatic burden and higher morbidity, as noted by… read more here.
Keywords: death; failure patients; sudden cardiac; heart failure ... See more keywords
Role of angiotensin‐converting enzyme insertion/deletion polymorphism in sudden cardiac arrest
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27622
Abstract: This study aimed to investigate the relationship between angiotensin‐converting enzyme (ACE) insertion/deletion (I/D) polymorphism and to understand sudden cardiac arrest (SCA) in the Chinese population. read more here.
Keywords: sudden cardiac; deletion polymorphism; insertion deletion; converting enzyme ... See more keywords
Molecular autopsy and clinical family screening in a case of sudden cardiac death reveals ACTN2 mutation related to hypertrophic/dilated cardiomyopathy and a novel LZTR1 variant associated with Noonan syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.1954
Abstract: Genetic cardiac diseases are the main trigger of sudden cardiac death (SCD) in young adults. Hypertrophic cardiomyopathy (HCM) is the most prevalent cardiomyopathy and accounts for 0.5 to 1% of SCD cases per year. read more here.
Keywords: autopsy clinical; cardiac death; sudden cardiac; molecular autopsy ... See more keywords
Arrhythmias and sudden cardiac death in the COVID-19 pandemic
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DOI: 10.1007/s00059-020-04924-0
Abstract: Coronavirus disease 2019 (COVID19) is a global pandemic with almost 2 million infections confirmed worldwide and close to 120,000 deaths; the estimated mortality rate ranges from continent to continent between 3 and 9% (as of… read more here.
Keywords: arrhythmias sudden; cardiac death; sudden cardiac; covid pandemic ... See more keywords
Supraventricular Tachycardia Without Preexcitation as a Cause of Sudden Cardiac Arrest in Pediatric Patients
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DOI: 10.1007/s00246-021-02720-z
Abstract: Sudden cardiac arrest in pediatric patients is a rare occurrence. Supraventricular tachycardia without the presence of ventricular preexcitation in pediatric patients with a structurally normal heart is generally considered benign. Previous literature in adults reported… read more here.
Keywords: etiology; sudden cardiac; tachycardia; cardiac arrest ... See more keywords
Questionnaire in patients with aborted sudden cardiac death due to coronary spasm in Japan
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DOI: 10.1007/s00380-020-01644-7
Abstract: We investigated the medical or mechanical therapy, and the present knowledge of Japanese cardiologists about aborted sudden cardiac death (ASCD) due to coronary spasm. A questionnaire was developed regarding the number of cases of ASCD,… read more here.
Keywords: coronary spasm; ascd due; sudden cardiac; due coronary ... See more keywords
Postmortem genetic testing should be recommended in sudden cardiac death cases due to thoracic aortic dissection
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DOI: 10.1007/s00414-017-1583-9
Abstract: BackgroundAcute thoracic aortic dissections and ruptures, the main life-threatening complications of the corresponding aneurysms, are an important cause of sudden cardiac death. Despite the usefulness of the molecular diagnosis of these conditions in the clinical… read more here.
Keywords: thoracic aortic; sudden cardiac; cardiac death; aortic dissection ... See more keywords