Advances and Challenges in Bioprocess Optimization for the Synthesis of Sugar Nucleotides
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DOI: 10.1002/cbic.202500434
Abstract: Sugar nucleotides represent the cornerstone building blocks for glycan biosynthesis. While methods to access these crucial biomolecules using traditional batch synthetic chemistry and enzymatic approaches have blossomed, uptake using flow‐based synthesis is burgeoning. This perspective… read more here.
Keywords: sugar nucleotides; sugar; bioprocess optimization; advances challenges ... See more keywords
Characterisation of sugar nucleotides in colostrum of dairy domestic farms animals
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DOI: 10.1016/j.idairyj.2020.104897
Abstract: Abstract The biological significance and heterogeneity of bovine, caprine and ovine colostrum sugar nucleotides is unclear. Colostrum sugar nucleotides and sugar monophosphates were purified and characterised with 1H-NMR spectroscopy. UDP-galactose (UDP-Gal) and UDP-glucose (UDP-Glc) were… read more here.
Keywords: sugar; nucleotides colostrum; sugar nucleotides; dairy domestic ... See more keywords
Gram-scale production of sugar nucleotides and their derivatives
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DOI: 10.1039/d1gc00711d
Abstract: Here, we report a practical sugar nucleotide production strategy that combined a high-concentrated multi-enzyme catalyzed reaction and a robust chromatography-free selective precipitation purification process. Twelve sugar nucleotides were synthesized on a gram scale with a… read more here.
Keywords: gram scale; sugar; sugar nucleotides; production sugar ... See more keywords