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Published in 2022 at "Glycobiology"
DOI: 10.1093/glycob/cwac085
Abstract: During our biochemical characterization of select bacterial phosphatases belonging to the haloacid dehalogenase (HAD) superfamily of hydrolases, we discovered a strong bias of Salmonella YidA for glucose-1-phosphate (Glc-1-P) over galactose-1-phosphate (Gal-1-P). We sought to exploit…
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Keywords:
phosphate;
galactose phosphate;
yida;
phosphate phosphatases ... See more keywords
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Published in 2022 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/erac386
Abstract: Abstract Regulating the central CO2-fixing enzyme Rubisco is as complex as its ancient reaction mechanism and involves interaction with a series of cofactors and auxiliary proteins that activate catalytic sites and maintain activity. A key…
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Keywords:
phosphate;
phosphate derivatives;
rubisco;
regulation ... See more keywords
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Published in 2022 at "Journal of Bacteriology"
DOI: 10.1128/jb.00344-22
Abstract: Bacterial pathogens are becoming increasingly resistant to antibiotics. There is an urgent need to identify novel drug targets and therapeutic strategies. ABSTRACT Pathogens are becoming resistant to antimicrobials at an increasing rate, and novel therapeutic…
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Keywords:
sugar;
phosphate toxicities;
salmonella;
sugar phosphate ... See more keywords