Accelerated extrinsic epigenetic aging and increased natural killer cells in blood of suicide completers
Sign Up to like & getrecommendations! Published in 2020 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2019.109805
Abstract: BACKGROUND Studies suggest aberrant DNA methylation in victims of suicide. Recently, DNA methylation profiles have been developed for determining "epigenetic age," which is the most accurate estimate of biological age. Subsequently, two refined measures of… read more here.
Keywords: suicide completers; epigenetic aging; blood; extrinsic epigenetic ... See more keywords
Loss of chromosome Y in blood, but not in brain, of suicide completers
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0190667
Abstract: Men have a higher rate of completed suicide than women, which suggests that sex chromosome abnormalities may be related to the pathophysiology of suicide. Recent studies have found an aberrant loss of chromosome Y (LOY)… read more here.
Keywords: suicide completers; loy; blood; brain ... See more keywords