In vitro activity of cefiderocol and sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii clinical isolates collected between 2019 and 2024.
Sign Up to like & getrecommendations! Published in 2025 at "Infectious diseases"
DOI: 10.1080/23744235.2025.2597465
Abstract: BACKGROUND The management of Acinetobacter baumannii infections has become increasingly challenging due to extensive antimicrobial resistance. OBJECTIVES This study evaluated the in vitro activity of cefiderocol and sulbactam-durlobactam and characterised OXA-type enzyme diversity in carbapenem-resistant A.… read more here.
Keywords: sulbactam durlobactam; cefiderocol; baumannii; carbapenem resistant ... See more keywords
Clinical Outcomes for Patients With Monomicrobial vs Polymicrobial Acinetobacter baumannii-calcoaceticus Complex Infections Treated With Sulbactam-Durlobactam or Colistin: A Subset Analysis From a Phase 3 Clinical Trial
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DOI: 10.1093/ofid/ofae140
Abstract: Abstract Background In a previous study, the efficacy and safety of sulbactam-durlobactam vs colistin for the treatment of patients with carbapenem-resistant Acinetobacter baumannii-calcoaceticus complex (CRABC) infections were evaluated in a randomized controlled phase 3 trial.… read more here.
Keywords: monomicrobial polymicrobial; sulbactam durlobactam; durlobactam; baumannii calcoaceticus ... See more keywords
Acinetobacter baumannii Resistance to Sulbactam/Durlobactam: A Systematic Review
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DOI: 10.3390/antibiotics11121793
Abstract: Infections caused by carbapenem-resistant Acinetobacter baumannii (CRAB) have limited therapeutic options. Sulbactam-durlobactam is a combination of two βlactamase inhibitors with activity against CRAB under phase 3 clinical investigation. We performed a systematic review on in… read more here.
Keywords: sulbactam durlobactam; systematic review; acinetobacter baumannii; resistance ... See more keywords