S Marks the Spot: Linking the Antioxidant Activity of N-Acetyl Cysteine to H2S and Sulfane Sulfur Species.
Sign Up to like & getrecommendations! Published in 2018 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2018.04.001
Abstract: N-Acetyl cysteine (NAC) is commonly used as an antioxidant and cytoprotectant, yet a broadly applicable mechanism of these activities has remained elusive. In this issue of Cell Chemical Biology, Ezeriņa et al. (2018) report an alternative… read more here.
Keywords: antioxidant activity; acetyl cysteine; sulfane sulfur; biology ... See more keywords
Stabilities of Three Key Biological Trisulfides with Implications for Their Roles in the Release of Hydrogen Sulfide and Bioaccumulation of Sulfane Sulfur
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DOI: 10.1021/acsomega.2c00736
Abstract: Trisulfides and higher polysulfides are important in the body due to their function as key reservoirs of sulfane sulfur and their rapid reactions to release persulfides. Recent work has shown that persulfides act as powerful… read more here.
Keywords: release hydrogen; spectroscopy; hydrogen sulfide; sulfur ... See more keywords
Supramolecular Activation of S8 by Cucurbiturils in Water and Mechanism of Reduction to H2S by Thiols: Insights into Biological Sulfane Sulfur Trafficking.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c06332
Abstract: Reactive sulfur species (RSS) play critical roles in diverse chemical environments. Molecules containing sulfane sulfur (S0) have emerged as key species involved in cellular redox buffering as well as RSS generation, translocation, and action. Using… read more here.
Keywords: mechanism; sulfane sulfur; reduction h2s; sulfur ... See more keywords
Sulfane sulfur‐activated actinorhodin production and sporulation is maintained by a natural gene circuit in Streptomyces coelicolor
Sign Up to like & getrecommendations! Published in 2020 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.13637
Abstract: Sulfane sulfur, including polysulfide and persulfide, is a newly identified cellular component present in microorganisms; however, its physiological functions are unclear. Streptomyces coelicolor M145 is a model strain of actinomycetes, which produces several polyketides, including… read more here.
Keywords: actinorhodin production; sulfane sulfur; gene; sulfane ... See more keywords
Synechococcus sp. PCC7002 Uses Peroxiredoxin to Cope with Reactive Sulfur Species Stress
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01039-22
Abstract: Cyanobacteria are the earliest microorganisms that perform oxygenic photosynthesis, which has played a key role in the evolution of life on Earth, and they are the most important primary producers in the modern oceans. The… read more here.
Keywords: synechococcus pcc7002; sulfane sulfur; sulfur;
Sulfane Sulfur Posttranslationally Modifies the Global Regulator AdpA to Influence Actinorhodin Production and Morphological Differentiation of Streptomyces coelicolor
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DOI: 10.1128/mbio.03862-21
Abstract: Streptomyces species produce a myriad of natural products with (potential) clinical applications. While the database of biosynthetic gene clusters is quickly expanding, their regulation mechanisms are rarely known. ABSTRACT The transcription factor AdpA is a… read more here.
Keywords: gene; morphological differentiation; sulfane sulfur; sulfur ... See more keywords
Sulfane Sulfur Is an Intrinsic Signal for the Organic Peroxide Sensor OhrR of Pseudomonas aeruginosa
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11091667
Abstract: Sulfane sulfur, including organic persulfide and polysulfide, is a normal cellular component, and its level varies during growth. It is emerging as a signaling molecule in bacteria, regulating the gene regulator MarR in Escherichia coli,… read more here.
Keywords: sulfane; sulfane sulfur; pseudomonas aeruginosa; expression ... See more keywords
The Pleiotropic Regulator AdpA Regulates the Removal of Excessive Sulfane Sulfur in Streptomyces coelicolor
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12020312
Abstract: Reactive sulfane sulfur (RSS), including persulfide, polysulfide, and elemental sulfur (S8), has important physiological functions, such as resisting antibiotics in Pseudomonas aeruginosa and Escherichia coli and regulating secondary metabolites production in Streptomyces spp. However, at… read more here.
Keywords: sulfane sulfur; adpa; regulator; rss ... See more keywords
The Transcriptional Repressor PerR Senses Sulfane Sulfur by Cysteine Persulfidation at the Structural Zn2+ Site in Synechococcus sp. PCC7002
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12020423
Abstract: Cyanobacteria can perform both anoxygenic and oxygenic photosynthesis, a characteristic which ensured that these organisms were crucial in the evolution of the early Earth and the biosphere. Reactive oxygen species (ROS) produced in oxygenic photosynthesis… read more here.
Keywords: sulfane sulfur; repressor perr; transcriptional repressor; site ... See more keywords
Organelle-Targeted Fluorescent Probes for Sulfane Sulfur Species
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DOI: 10.3390/antiox12030590
Abstract: Sulfane sulfurs, which include hydropersulfides (RSSH), hydrogen polysulfides (H2Sn, n > 1), and polysulfides (RSnR, n > 2), play important roles in cellular redox biology and are closely linked to hydrogen sulfide (H2S) signaling. While… read more here.
Keywords: sulfane sulfur; sulfur species; targeted fluorescent; organelle targeted ... See more keywords
The Rhodanese PspE Converts Thiosulfate to Cellular Sulfane Sulfur in Escherichia coli
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12051127
Abstract: Hydrogen sulfide (H2S) and its oxidation product zero-valent sulfur (S0) play important roles in animals, plants, and bacteria. Inside cells, S0 exists in various forms, including polysulfide and persulfide, which are collectively referred to as… read more here.
Keywords: sulfane sulfur; cellular sulfane; sulfur; thiosulfate cellular ... See more keywords