LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "sulfatase" as a keyword



Photo from wikipedia

Inhibition of endogenous miR‐23a/miR‐377 in CHO cells enhances difficult‐to‐express recombinant lysosomal sulfatase activity

Sign Up to like & get
recommendations! Published in 2020 at "Biotechnology Progress"

DOI: 10.1002/btpr.2974

Abstract: Difficult‐to‐express (DTE) recombinant proteins such as multi‐specific proteins, DTE monoclonal antibodies, and lysosomal enzymes have seen difficulties in manufacturability using Chinese hamster ovary (CHO) cells or other mammalian cells as production platforms. CHO cells are… read more here.

Keywords: mir 23a; sulfatase; cho cells; mir ... See more keywords
Photo by yapics from unsplash

2‐Difluoromethoxy‐Substituted Estratriene Sulfamates: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Steroid Sulfatase Inhibition

Sign Up to like & get
recommendations! Published in 2022 at "ChemMedChem"

DOI: 10.1002/cmdc.202200408

Abstract: 2‐Difluoromethoxyestratriene derivatives were designed to improve potency and in vivo stability of the drug candidate 2‐methoxyestradiol (2ME2). Compound evaluation in vitro against the proliferation of MCF‐7 and MDA MB‐231 breast cancer cells, as inhibitors of tubulin polymerisation… read more here.

Keywords: difluoromethoxy substituted; steroid sulfatase; inhibition; substituted estratriene ... See more keywords
Photo by nofish from unsplash

Sulfatase‐mediated manipulation of the astrocyte‐Schwann cell interface

Sign Up to like & get
recommendations! Published in 2017 at "Glia"

DOI: 10.1002/glia.23047

Abstract: Schwann cell (SC) transplantation following spinal cord injury (SCI) may have therapeutic potential. Functional recovery is limited however, due to poor SC interactions with host astrocytes and the induction of astrogliosis. Olfactory ensheathing cells (OECs)… read more here.

Keywords: sulfatase mediated; sulfatase; astrocyte; schwann cell ... See more keywords
Photo by shelbymdesign from unsplash

Activatable Near-Infrared Fluorescent and Photoacoustic Dual-Modal Probe for Highly Sensitive Imaging of Sulfatase In Vivo.

Sign Up to like & get
recommendations! Published in 2023 at "ACS sensors"

DOI: 10.1021/acssensors.3c00201

Abstract: Sulfatase is an important biomarker closely associated with various diseases. However, the state-of-the-art sulfatase probes are plagued with a short absorption/emission wavelength and limited sensitivity. Developing highly sensitive fluorescent probes for in vivo imaging of… read more here.

Keywords: dual modal; sulfatase; highly sensitive; imaging sulfatase ... See more keywords
Photo by niaid from unsplash

Dopamine-induced sulfatase and its regulator are required for Salmonella enterica serovar Typhimurium pathogenesis.

Sign Up to like & get
recommendations! Published in 2019 at "Microbiology"

DOI: 10.1099/mic.0.000769

Abstract: Catecholamine hormones enhance the virulence of pathogenic bacteria. Studies in the 1980s made intriguing observations that catecholamines were required for induction of sulfatase activity in many enteric pathogens, including Salmonella enterica serovar Typhimurium. In this… read more here.

Keywords: sulfatase; induced sulfatase; serovar typhimurium; typhimurium ... See more keywords
Photo by chrostek from unsplash

Structure and expression of sulfatase and sulfatase modifying factor genes in the diamondback moth, Plutella xylostella

Sign Up to like & get
recommendations! Published in 2018 at "Insect Science"

DOI: 10.1111/1744-7917.12487

Abstract: The diamondback moth, Plutella xylostella (L.), uses sulfatases (SULF) to counteract the glucosinolate–myrosinase defensive system that cruciferous plants have evolved to deter insect feeding. Sulfatase activity is regulated by post‐translational modification of a cysteine residue… read more here.

Keywords: xylostella; sulfatase; modifying factor; expression ... See more keywords
Photo by nci from unsplash

Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency

Sign Up to like & get
recommendations! Published in 2023 at "EMBO Molecular Medicine"

DOI: 10.15252/emmm.202114837

Abstract: Multiple sulfatase deficiency (MSD, MIM #272200) results from pathogenic variants in the SUMF1 gene that impair proper function of the formylglycine‐generating enzyme (FGE). FGE is essential for the posttranslational activation of cellular sulfatases. MSD patients… read more here.

Keywords: tazarotene bexarotene; sulfatase; sulfatase deficiency; multiple sulfatase ... See more keywords
Photo by niaid from unsplash

Sulfatase-2 Regulates Liver Fibrosis through the TGF-β Signaling Pathway

Sign Up to like & get
recommendations! Published in 2021 at "Cancers"

DOI: 10.3390/cancers13215279

Abstract: Simple Summary Liver fibrosis and/or cirrhosis is a major risk factor for hepatocellular carcinoma. Hepatic Fibrogenesis is the result of an excessive production and deposition of extracellular matrix by hepatic myofibroblasts, which are primarily formed… read more here.

Keywords: sulf2; fibrosis; sulfatase; liver fibrosis ... See more keywords
Photo by cdc from unsplash

Clinical significance of the estrogen-modifying enzymes steroid sulfatase and estrogen sulfotransferase in epithelial ovarian cancer

Sign Up to like & get
recommendations! Published in 2017 at "Oncology Letters"

DOI: 10.3892/ol.2017.5969

Abstract: 17β-estradiol (E2) can contribute to the progression of epithelial ovarian cancer (EOC). Although the majority of patients with EOC are postmenopausal woman, when de novo estrogen production in the ovary has ceased, ovarian cancer cells… read more here.

Keywords: sult1e1; epithelial ovarian; sulfatase; estrogen ... See more keywords