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Published in 2017 at "ACS chemical biology"
DOI: 10.1021/acschembio.6b01033
Abstract: The degradation of glycosaminoglycans (GAGs) involves a series of exolytic glycosidases and sulfatases that act sequentially on the nonreducing end of the polysaccharide chain. Enzymes have been cloned that catalyze all of the known linkages…
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Keywords:
sulfoglucuronate;
sulfatase arylsulfatase;
arylsulfatase lysosomal;
arylsulfatase ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232113146
Abstract: The enzyme N-acetylgalactosamine-4-sulfatase (Arylsulfatase B; ARSB) was originally identified as a lysosomal enzyme which was deficient in Mucopolysaccharidosis VI (MPS VI; Maroteaux-Lamy Syndrome). The newly directed attention to the impact of ARSB in human pathobiology…
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Keywords:
sulfatase arylsulfatase;
human diseases;
acetylgalactosamine sulfatase;
impact decline ... See more keywords