A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation
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DOI: 10.1093/glycob/cwac004
Abstract: Abstract NDST1 (glucosaminyl N-deacetylase/N-sulfotransferase) is a key enzyme in heparan sulfate (HS) biosynthesis, where it is responsible for HS N-deacetylation and N-sulfation. In addition to the full length human enzyme of 882 amino acids, here… read more here.
Keywords: sulfation; heparan sulfate; sulfate biosynthesis; enzyme ... See more keywords