Convergent chemoenzymatic synthesis and biological evaluation of a heparan sulfate proteoglycan syndecan-1 mimetic.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc00796c
Abstract: A new convergent chemoenzymatic synthesis strategy, integrating enzymatic synthesis of heparan sulfate, sortase A ligation, copper(i)-catalyzed alkyne-azide cycloaddition, and solid phase peptide synthesis, has been established to efficiently synthesize a mimetic of heparan sulfate proteoglycan… read more here.
Keywords: convergent chemoenzymatic; synthesis; sulfate proteoglycan; heparan sulfate ... See more keywords
Regulation of morphogen pathways by a Drosophila chondroitin sulfate proteoglycan Windpipe.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cell science"
DOI: 10.1242/jcs.260525
Abstract: Morphogens provide quantitative and robust signaling systems to achieve stereotypic patterning and morphogenesis. Heparan sulfate proteoglycans (HSPGs) are key components of such regulatory feedback networks. In Drosophila, HSPGs serve as co-receptors for a number of… read more here.
Keywords: morphogen pathways; regulation morphogen; morphogen; sulfate proteoglycan ... See more keywords
The Association between Genes Polymorphisms of Heparan Sulfate Proteoglycan 2 (HSPG2) and Chondroitin Sulfate Proteoglycan 2 (CSPG2) and Intracranial Aneurysm Susceptibility: A Meta-Analysis
Sign Up to like & getrecommendations! Published in 2019 at "Iranian Journal of Public Health"
DOI: 10.18502/ijph.v48i11.3512
Abstract: Background: We aimed to investigate whether the polymorphisms of gene heparan sulfate proteoglycan 2 (HSPG2) and chondroitin sulfate proteoglycan 2 (CSPG2) are associated with increased risk of intracranial aneurysms (IAs) susceptibility. Methods: The Cochrane Library,… read more here.
Keywords: cspg2; heparan sulfate; susceptibility; hspg2 ... See more keywords
Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types
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DOI: 10.3389/fimmu.2017.01911
Abstract: Overexpression of the chondroitin sulfate proteoglycan 4 (CSPG4) has been associated with the pathology of multiple types of such as melanoma, breast cancer, squamous cell carcinoma, mesothelioma, neuroblastoma, adult and pediatric sarcomas, and some hematological… read more here.
Keywords: antibody; proteoglycan potential; target; chondroitin sulfate ... See more keywords