Designing Synthetic, Sulfated Glycosaminoglycan Mimetics That Are Orally Bioavailable and Exhibiting In Vivo Anticancer Activity
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DOI: 10.1021/acs.jmedchem.2c01511
Abstract: Sulfated glycosaminoglycans (GAGs), or synthetic mimetics thereof, are not favorably viewed as orally bioavailable drugs owing to their high number of anionic sulfate groups. Devising an approach for oral delivery of such highly sulfated molecules… read more here.
Keywords: vivo anticancer; synthetic sulfated; orally bioavailable; sulfated gag ... See more keywords