On resin synthesis of sulfated oligosaccharides
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d1sc06063e
Abstract: Sulfated glycans are involved in many biological processes, making well-defined sulfated oligosaccharides highly sought molecular probes. These compounds are a considerable synthetic challenge, with each oligosaccharide target requiring specific synthetic protocols and extensive purifications steps.… read more here.
Keywords: sulfated oligosaccharides; synthesis sulfated; resin synthesis; sulfated glycans ... See more keywords
Inhibition of SARS-CoV-2 wild-type (Wuhan-Hu-1) and Delta (B.1.617.2) strains by marine sulfated glycans
Sign Up to like & getrecommendations! Published in 2022 at "Glycobiology"
DOI: 10.1093/glycob/cwac042
Abstract: Abstract The Coronavirus disease pandemic has steered the global therapeutic research efforts toward the discovery of potential anti-severe acute respiratory syndrome coronavirus (SARS-CoV-2) molecules. The role of the viral spike glycoprotein (S-protein) has been clearly… read more here.
Keywords: type wuhan; wuhan delta; sars cov; marine sulfated ... See more keywords
Distinct sulfated glycans expressed in intrahepatic cholangiocarcinoma: a potential target for new therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Immunotherapy"
DOI: 10.2217/imt-2022-0220
Abstract: Cholangiocytes exhibit morphological and functional heterogeneity, depending on their anatomical localization; however, like other ductal organs, their mucosal surface is covered with mucin, which functions to prevent the entry of foreign substances, lubricate and prevent clogging… read more here.
Keywords: glycans expressed; expressed intrahepatic; intrahepatic cholangiocarcinoma; distinct sulfated ... See more keywords
Interactions of marine sulfated glycans with antithrombin and platelet factor 4
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.954752
Abstract: The molecular interactions of sulfated glycans, such as heparin, with antithrombin (AT) and platelet factor 4 (PF4) are essential for certain biological events such as anticoagulation and heparin induced thrombocytopenia (HIT). In this study, a… read more here.
Keywords: platelet factor; antithrombin platelet; sulfated glycans; molecular weight ... See more keywords
SPR Sensor-Based Analysis of the Inhibition of Marine Sulfated Glycans on Interactions between Monkeypox Virus Proteins and Glycosaminoglycans
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DOI: 10.3390/md21050264
Abstract: Sulfated glycans from marine organisms are excellent sources of naturally occurring glycosaminoglycan (GAG) mimetics that demonstrate therapeutic activities, such as antiviral/microbial infection, anticoagulant, anticancer, and anti-inflammation activities. Many viruses use the heparan sulfate (HS) GAG… read more here.
Keywords: inhibition; monkeypox virus; mpxv a29; marine sulfated ... See more keywords
Complementary Role of GlcNAc6ST2 and GlcNAc6ST3 in Synthesis of CL40-Reactive Sialylated and Sulfated Glycans in the Mouse Pleural Mesothelium
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27144543
Abstract: Sialyl 6-sulfo Lewis X (6-sulfo sLeX) and its derivative sialyl 6-sulfo N-acetyllactosamine (LacNAc) are sialylated and sulfated glycans of sialomucins found in the high endothelial venules (HEVs) of secondary lymphoid organs. A component of 6-sulfo… read more here.
Keywords: cl40; glcnac6st2 glcnac6st3; sialylated sulfated; sulfated glycans ... See more keywords