A Cyclodiaryliodonium NOX Inhibitor for the Treatment of Pancreatic Cancer Via Enzyme-activatable Targeted Delivery by Sulfated Glycosaminoglycan Derivatives.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203011
Abstract: Pancreatic cancer renders a principal cause of cancer mortalities with a dismal prognosis, lacking sufficiently safe and effective therapeutics. Here, we rationally design diversified cyclodiaryliodonium NADPH oxidase (NOX) inhibitors with tens of nanomolar optimal growth… read more here.
Keywords: pancreatic cancer; glycosaminoglycan derivatives; sulfated glycosaminoglycan; cancer ... See more keywords
Effects of a sulfated glycosaminoglycan from Sepia esculenta ink on transcriptional and metabolic profiles of Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2022 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.118715
Abstract: Four fractions of water-extracted Sepia esculenta ink polysaccharides (SIP) were separated by dicthylaminoethy (DEAE) cellulose chromatography. The eluted fraction with the highest yield was characterized as a sulfate-rich glycosaminoglycan named SIP-IV. According to the analysis… read more here.
Keywords: saccharomyces cerevisiae; sepia esculenta; effects sulfated; esculenta ink ... See more keywords