Sulfated Alginate as a Mimic of Sulfated Glycosaminoglycans: Binding of Growth Factors and Effect on Stem Cell Behavior
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Biosystems"
DOI: 10.1002/adbi.201700043
Abstract: Sulfated glycosaminoglycans (GAGs) are principal elements of the extracellular matrix, where they are involved in a plethora of signaling pathways mainly via interactions with diverse proteins such as growth factors and cytokines. However, the mechanisms… read more here.
Keywords: cell; cell behavior; growth factors; stem cell ... See more keywords
Studies on European eel skin sulfated glycosaminoglycans: Recovery, structural characterization and anticoagulant activity.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.04.125
Abstract: Abstract The goal of the present work was the extraction and structural characterization of novel sulfated glycosaminoglycans from European eel skin. The recovered glycosaminoglycans were physicochemically characterized and the uronic acid and sulfate contents were… read more here.
Keywords: anticoagulant activity; european eel; structural characterization; activity ... See more keywords
Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells
Sign Up to like & getrecommendations! Published in 2019 at "Nature microbiology"
DOI: 10.1038/s41564-019-0464-z
Abstract: Clostridium difficile toxin A (TcdA) is a major exotoxin contributing to disruption of the colonic epithelium during C. difficile infection. TcdA contains a carbohydrate-binding combined repetitive oligopeptides (CROPs) domain that mediates its attachment to cell… read more here.
Keywords: clostridium difficile; tcda; low density; difficile toxin ... See more keywords
The COVID‐19 vaccine ChAdOx1‐S is not contaminated with sulfated glycosaminoglycans
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.15633
Abstract: Vaccination against severe acute respiratory syndrome coronavirus 2 (SARSCoV2) is one of the most important measures to fight the coronavirus 2019 (COVID19) pandemic. One of the vaccines, ChAdOx1S (AstraZeneca), is a recombinant, replicationdeficient chimpanzee adenovirus… read more here.
Keywords: chadox1 contaminated; covid vaccine; vaccine chadox1; sulfated glycosaminoglycans ... See more keywords
High-Sulfated Glycosaminoglycans Prevent Coronavirus Replication
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14020413
Abstract: Coronaviruses (CoVs) are common among humans and many animals, causing respiratory or gastrointestinal diseases. Currently, only a few antiviral drugs against CoVs are available. Especially for SARS-CoV-2, new compounds for treatment of COVID-19 are urgently… read more here.
Keywords: effect; high sulfated; sulfated glycosaminoglycans; prevent coronavirus ... See more keywords