A molecular dynamics-based algorithm for evaluating the glycosaminoglycan mimicking potential of synthetic, homogenous, sulfated small molecules
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DOI: 10.1371/journal.pone.0171619
Abstract: Glycosaminoglycans (GAGs) are key natural biopolymers that exhibit a range of biological functions including growth and differentiation. Despite this multiplicity of function, natural GAG sequences have not yielded drugs because of problems of heterogeneity and… read more here.
Keywords: based algorithm; molecular dynamics; step; sulfated nsgms ... See more keywords