The role of sulfenic acids in cellular redox signaling: Reconciling chemical kinetics and molecular detection strategies.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2017.01.008
Abstract: The reversible oxidation of protein cysteine residues is well recognized as an important regulatory mechanism in redox-dependent cell signaling. Cysteine oxidation is diverse in nature and involves various post-translational modifications (sulfenic acids, disulfides, etc.) and… read more here.
Keywords: oxidation; cys soh; redox; cysteine oxidation ... See more keywords
Reactions of sulfenic acids with amines, thiols, and thiolates studied by quantum chemical calculations
Sign Up to like & getrecommendations! Published in 2020 at "Computational and Theoretical Chemistry"
DOI: 10.1016/j.comptc.2020.112979
Abstract: Abstract Biological sensor molecules for oxidative stress often rely on the oxidation of thiols to sulfenic acid intermediates. How this transformation induces a physiological response often relies on the fate of sulfenic acid. Sulfenic acids… read more here.
Keywords: acids amines; amines thiols; reactions sulfenic; thiols thiolates ... See more keywords
Trapping Reactions of the Sulfenyl and Sulfinyl Tautomers of Sulfenic Acids.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical biology"
DOI: 10.1021/acschembio.6b00980
Abstract: Sulfenic acids react as both nucleophiles and electrophiles, which may be attributable to interconversion between sulfenyl and sulfinyl tautomers. We demonstrate one-pot trapping of both tautomeric forms of glutathione sulfenic acid by LCMS. The sulfinyl… read more here.
Keywords: sulfenyl sulfinyl; reactions sulfenyl; sulfenic acids; trapping reactions ... See more keywords