Protein S-sulfhydration: Unraveling the prospective of hydrogen sulfide in the brain, vasculature and neurological manifestations
Sign Up to like & getrecommendations! Published in 2022 at "Ageing Research Reviews"
DOI: 10.1016/j.arr.2022.101579
Abstract: Hydrogen sulfide (H2S) and hydrogen polysulfides (H2Sn) are essential regulatory signaling molecules generated by the entire body, including the central nervous system. Researchers have focused on the classical H2S signaling from the past several decades,… read more here.
Keywords: hydrogen sulfide; sulfhydration; protein sulfhydration; h2s ... See more keywords
Hydrogen sulfide inhibited L-type calcium channels (CaV1.2) via up-regulation of the channel sulfhydration in vascular smooth muscle cells.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172455
Abstract: Hydrogen sulfide (H2S) exerts different effects on the cardiovascular system by modulating ion channels. The present study was to ascertain whether H2S affects L-type calcium (Ca2+) channels in vascular smooth muscle cells (VSMCs) and the… read more here.
Keywords: type calcium; vascular smooth; ca2; hydrogen sulfide ... See more keywords
Hydrogen sulfide promotes flowering in heading Chinese cabbage by S-sulfhydration of BraFLCs
Sign Up to like & getrecommendations! Published in 2021 at "Horticulture Research"
DOI: 10.1038/s41438-020-00453-3
Abstract: Heading Chinese cabbage (Brassica rapa L. syn. B. campestris L. ssp. chinensis Makino var. pekinensis (Rupr.) J. Cao et Sh. Cao) is a cruciferous Brassica vegetable that has a triplicate genome, owing to an ancient… read more here.
Keywords: chinese cabbage; heading chinese; braflc; sulfhydration ... See more keywords
Endothelial HDAC1-ZEB2-NuRD Complex Drives Aortic Aneurysm and Dissection Through Regulation of Protein S-Sulfhydration
Sign Up to like & getrecommendations! Published in 2023 at "Circulation"
DOI: 10.1161/circulationaha.122.062743
Abstract: Background: Aortic aneurysm and aortic dissection (AAD) are life-threatening vascular diseases, with endothelium being the primary target for AAD treatment. Protein S-sulfhydration is a newly discovered posttranslational modification whose role in AAD has not yet… read more here.
Keywords: protein sulfhydration; sulfhydration; nurd complex; aad ... See more keywords
H2S-Induced Sulfhydration: Biological Function and Detection Methodology
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2017.00608
Abstract: At appropriate concentrations, hydrogen sulfide, a well-known gasotransmitter, plays important roles in both physiology and pathophysiology. Increasing evidence suggests that modifying thiol groups of specific cysteines in target proteins via sulfhydration or persulfidation is one… read more here.
Keywords: induced sulfhydration; methodology; biological function; hydrogen sulfide ... See more keywords
H2S- and Redox-State-Mediated PTP1B S-Sulfhydration in Insulin Signaling
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032898
Abstract: Because hydrogen sulfide (H2S) is classified as a gaseous signaling molecule, protein S-sulfhydration is known to be one of the mechanisms by which H2S signals are conducted. PTP1B, a negative regulator in insulin signaling, has… read more here.
Keywords: sulfhydration; h2s redox; ptp1b sulfhydration; insulin signaling ... See more keywords