Sustained Release of Dexamethasone from Sulfobutyl Ether β-cyclodextrin Modified Self-Assembling Peptide Nanoscaffolds in a Perinatal Rat Model of Hypoxia-Ischemia.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201900083
Abstract: Inflammation plays a critical role in the development of hypoxia-ischemia (HI) induced newborn brain damage. A localized, sustained delivery of dexamethasone (Dex) through an intracerebral injection could reduce the inflammatory response in the injured perinatal… read more here.
Keywords: hypoxia ischemia; dex; sbe rada; sulfobutyl ether ... See more keywords
Effect of sulfobutyl ether-β-cyclodextrin and propylene glycol alginate on the solubility of clozapine
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2018.1514521
Abstract: Abstract Clozapine (CLZ) is an atypical antipsychotic medication used in the treatment of schizophrenia and is poorly soluble in water (0.05 mM). In this study, we have investigated the effect of β-cyclodextrin (CD) and its derivatives… read more here.
Keywords: clz; solubility clz; sulfobutyl ether; effect ... See more keywords
Development and physicochemical characterization of chitosan hydrochloride/sulfobutyl ether-β-cyclodextrin nanoparticles for cinnamaldehyde entrapment.
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DOI: 10.1111/jfbc.13197
Abstract: In this work, the cinnamaldehyde (CA) loaded nanoparticles were synthesized by directly cross-linking chitosan hydrochloride (CSH) and sulfobutyl ether-β-cyclodextrin (SBE-β-CD). The CA/SBE-β-CD inclusion complex was firstly prepared, and its highest encapsulation efficiency (EE) was 86.34%.… read more here.
Keywords: ether cyclodextrin; chitosan hydrochloride; csns; sulfobutyl ether ... See more keywords
Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters
Sign Up to like & getrecommendations! Published in 2023 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-023-02571-2
Abstract: The purpose of the study is to investigate the influence of sulfobutyl ether β-cyclodextrin (SBE_7-β-CD) on the bioavailability of valsartan. Phase solubility investigations showed an A_L type curve. The estimated apparent stability constant for valsartan… read more here.
Keywords: oral bioavailability; inclusion complex; bioavailability; inclusion ... See more keywords