Photolysis mechanism of sulfonamide moiety in five-membered sulfonamides: A DFT study.
Sign Up to like & getrecommendations! Published in 2018 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2018.01.041
Abstract: Quantum chemical calculations have been performed to investigate the photolysis mechanism of relatively susceptible sulfonamide moiety of five-membered sulfonamide (SA) antibiotics, such as sulfamethoxazole, sulfisoxazole, sulfamethizole, and sulfathiazole. The results show that the ·OH-mediated indirect… read more here.
Keywords: photolysis; photolysis mechanism; sulfonamide moiety; five membered ... See more keywords
First Discovery of Imidazo[1,2-a]pyridine Mesoionic Compounds Incorporating a Sulfonamide Moiety as Antiviral Agents.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c01813
Abstract: The applications of mesoionic compounds and their analogues as agents against plant viruses remain unexplored. This was the first evaluation of the antiviral activities of mesoionic compounds on this issue. Our study involved the design… read more here.
Keywords: mesoionic compounds; sulfonamide moiety; imidazo pyridine; pyridine mesoionic ... See more keywords
Design, Synthesis, and Biological Evaluation of Novel 1,4-Pentadien-3-one Derivatives Containing a Sulfonamide Moiety.
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DOI: 10.1021/acs.jafc.2c05731
Abstract: Novel 1,4-pentadien-3-one derivatives containing a sulfonamide moiety were synthesized, and their antifungal, antibacterial, and antiviral activities were verified. These compounds exhibited better activity against five bacteria, with EC50 values ranging from 9.6 to 60.1 μg/mL,… read more here.
Keywords: pentadien one; containing sulfonamide; derivatives containing; sulfonamide moiety ... See more keywords
Sulfonamide moiety as "molecular chimera" in the design of new drugs.
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DOI: 10.2174/0929867329666220729151500
Abstract: BACKGROUND The -SO2NH- group is of great significance in modern pharmaceutical use since in sulfa-drugs it is possible to introduce easily chemical modifications, and even small changes may lead to an improved version of an… read more here.
Keywords: sulfonamide moiety; design; moiety molecular; moiety ... See more keywords