Selective Covalent Targeting of Anti‐apoptotic BFL‐1 by a Sulfonium‐Tethered Peptide
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DOI: 10.1002/cbic.202000473
Abstract: Anti‐apoptotic B cell lymphoma 2 (BCL‐2) family proteins are proven targets for human cancers. Targeting the BH3‐binding pockets of these anti‐apoptotic proteins could reactivate apoptosis in BCL‐2‐depedent cancers. BFL‐1 is a BCL‐2 family protein overexpressed… read more here.
Keywords: sulfonium tethered; tethered peptide; bfl; anti apoptotic ... See more keywords