Activities of 11‐Azaartemisinin and N‐Sulfonyl Derivatives against Asexual and Transmissible Malaria Parasites
Sign Up to like & getrecommendations! Published in 2017 at "ChemMedChem"
DOI: 10.1002/cmdc.201700599
Abstract: Dihydroartemisinin (DHA), either used in its own right or as the active drug generated in vivo from the other artemisinins in current clinical use—artemether and artesunate—induces quiescence in ring‐stage parasites of Plasmodium falciparum (Pf). This induction… read more here.
Keywords: sulfonyl derivatives; asexual transmissible; azaartemisinin sulfonyl; activities azaartemisinin ... See more keywords
A convenient synthesis of (E)-conjugated polyene sulfonyl derivatives with excellent stereospecificity
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2018.05.060
Abstract: Abstract A highly selective synthesis of conjugated polyene sulfonyl derivatives is described via the elimination of disulfonyl chloride with readily accessible raw material dihaloalkane. The protocol offers a convenient way to form sulfonamides, sulfonates and… read more here.
Keywords: sulfonyl derivatives; synthesis conjugated; conjugated polyene; polyene sulfonyl ... See more keywords