Catalyst-controlled diastereoselective ring-opening formal [3+2]-cycloadditions of arylvinyl oxirane 2,2-diesters with cyclic N-sulfonyl imines
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DOI: 10.1007/s11426-019-9760-7
Abstract: A diastereoselectivity-controllable formal [3+2]-cycloaddition of arylvinyl oxirane 2,2-diesters with cyclic N-sulfonyl imines is developed, affording the corresponding tricyclic oxazolidine derivatives in moderate to excellent yields with excellent diastereoselectivities in the presence of palladium(0) or scandium(III)… read more here.
Keywords: catalyst controlled; sulfonyl imines; oxirane diesters; cyclic sulfonyl ... See more keywords
Nickel-Catalyzed Asymmetric Transfer Hydrogenation and α-Selective Deuteration of N-Sulfonyl Imines with Alcohols: Access to α-Deuterated Chiral Amines.
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DOI: 10.1021/acs.orglett.0c02921
Abstract: A nickel-catalyzed enantioselective transfer hydrogenation and deuteration of N-sulfonyl imines was developed. Excellent α-selectivity and high deuterium content were achieved by using inexpensive 2-propanol-d8 as a deuterium source. As a highlight, no deuteration of β-C-H… read more here.
Keywords: deuteration sulfonyl; sulfonyl imines; deuteration; transfer hydrogenation ... See more keywords