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   Articles with "sulfonylurea hybrids" as a keyword



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Design, Synthesis, Molecular Modeling and Anti-Hyperglycemic Evaluation of Quinazoline-Sulfonylurea Hybrids as Peroxisome Proliferator-Activated Receptor Gamma (PPARĪ³) and Sulfonylurea Receptor (SUR) Agonists

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23179605

Abstract: New quinazoline-sulfonylurea hybrids were prepared and examined for their in vivo anti-hyperglycemic activities in STZ-induced hyperglycemic rats using glibenclamide as a reference drug. Compounds VI-6-a, V, IV-4, VI-4-c, IV-6, VI-2-a, IV-1, and IV-2 were more… read more here.

Keywords: peroxisome proliferator; anti hyperglycemic; sulfonylurea hybrids; quinazoline sulfonylurea ... See more keywords