Abstract B26: Combinational effect of sulforaphane (SFN) and epigenetic demethylation agent 5-aza-2’-deoxycytidine (DAC) on metastatic melanoma
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DOI: 10.1158/1538-7445.mel2019-b26
Abstract: UV exposure-induced oxidative stress is implicated as the driving mechanism of melanoma development. Increased oxidative stress results in imbalanced reactive oxygen species (ROS) that damage DNA and dysregulated epigenetic modifications and leads to melanoma progression.… read more here.
Keywords: deoxycytidine dac; melanoma; aza deoxycytidine; sulforaphane sfn ... See more keywords