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   Articles with "sulfoxide reductase" as a keyword



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Methionine sulfoxide reductase A protects against lipopolysaccharide-induced septic shock via negative regulation of the proinflammatory responses.

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recommendations! Published in 2017 at "Archives of biochemistry and biophysics"

DOI: 10.1016/j.abb.2017.08.008

Abstract: Methionine sulfoxide reductase A (MsrA) is a major antioxidant enzyme that specifically catalyzes the reduction of methionine S-sulfoxide. In this study, we used MsrA gene-knockout (MsrA-/-) mice and bone marrow-derived macrophages (BMDMs) to investigate the… read more here.

Keywords: sulfoxide reductase; msra; lps induced; msra mice ... See more keywords
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Methionine sulfoxide reductase B1 regulates proliferation and invasion by affecting mitogen-activated protein kinase pathway and epithelial-mesenchymal transition in u2os cells.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.01.151

Abstract: Methionine sulfoxide reductase B1 (MsrB1), a member of the selenoprotein family and contributes significantly to the reduction of methionine sulfoxides produced from reactive oxygen species (ROS). However, few studies have examined the role of MsrB1… read more here.

Keywords: sulfoxide reductase; proliferation invasion; invasion; u2os cells ... See more keywords

A methionine-R-sulfoxide reductase, OsMSRB5, is required for rice defense against copper toxicity

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recommendations! Published in 2018 at "Environmental and Experimental Botany"

DOI: 10.1016/j.envexpbot.2018.04.006

Abstract: Abstract Methionine sulfoxide reductases (MSRs), a family of enzymes catalyzing the conversion of methionine from its oxidized form into its reduced form, has a pivotal role in responding to oxidative stress. In the present study,… read more here.

Keywords: sulfoxide reductase; rice; methionine; copper ... See more keywords
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Myristoylated Methionine Sulfoxide Reductase A Interacts with the Lipid-Binding Protein

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recommendations! Published in 2017 at "Free Radical Biology and Medicine"

DOI: 10.1016/j.freeradbiomed.2017.10.031

Abstract: Reactive oxygen species (ROS) are produced by a variety of cellular processes including metabolic activity, mitochondria, cellular signaling, and oncogene activity. Methionine sulfoxide reductase A (MsrA) is an antioxidant enzyme that can reduce methionine sulfoxide… read more here.

Keywords: protein; sulfoxide reductase; myristoylated msra; stard3 ... See more keywords
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Drosophila Methionine sulfoxide reductase A is not a methionine oxidase

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recommendations! Published in 2017 at "Free Radical Biology and Medicine"

DOI: 10.1016/j.freeradbiomed.2017.10.043

Abstract: Methionine sulfoxide reductase A (MsrA) stereospecifically catalyzes the reduction of S-methionine sulfoxide to methionine and is important in defense against oxidative stress. Recently, we reported that mammalian methionine sulfoxide reductase A stereospecifically and selectively oxidizes… read more here.

Keywords: drosophila; sulfoxide reductase; methionine; methionine oxidase ... See more keywords
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Abscisic acid-dependent nitric oxide pathway and abscisic acid-independent nitric oxide routes differently modulate NaCl stress induction of the gene expression of methionine sulfoxide reductase A and B in rice roots.

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recommendations! Published in 2018 at "Journal of plant physiology"

DOI: 10.1016/j.jplph.2018.10.019

Abstract: The methionine residues of proteins are the preferred targets of oxidation by reactive oxygen species resulting in the formation of methionine sulfoxide (MetSO), which impairs protein function. Methionine sulfoxide reductase A and B (MSR) catalyze… read more here.

Keywords: sulfoxide reductase; abscisic acid; expression; nitric oxide ... See more keywords
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Discovery and Rational Mutagenesis of Methionine Sulfoxide Reductase Biocatalysts To Expand the Substrate Scope of the Kinetic Resolution of Chiral Sulfoxides

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recommendations! Published in 2023 at "ACS Catalysis"

DOI: 10.1021/acscatal.3c00372

Abstract: Methionine sulfoxide reductase A (MsrA) enzymes have recently found applications as nonoxidative biocatalysts in the enantioselective kinetic resolution of racemic sulfoxides. This work describes the identification of selective and robust MsrA biocatalysts able to catalyze… read more here.

Keywords: chiral sulfoxides; expand substrate; sulfoxide reductase; resolution ... See more keywords

A conserved R type Methionine Sulfoxide Reductase reverses oxidized GrpEL1/Mge1 to regulate Hsp70 chaperone cycle

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recommendations! Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-21083-9

Abstract: Cells across evolution employ reversible oxidative modification of methionine and cysteine amino acids within proteins to regulate responses to redox stress. Previously we have shown that mitochondrial localized methionine sulfoxide reductase (Mxr2) reversibly regulates oxidized… read more here.

Keywords: sulfoxide reductase; methionine; mge1; methionine sulfoxide ... See more keywords

Chalcogen-based ratiometric reversible BODIPY redox sensors for the determination of enantioselective methionine sulfoxide reductase activity.

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recommendations! Published in 2022 at "Chemical communications"

DOI: 10.1039/d2cc02016e

Abstract: Many serious diseases are associated with degenerative changes caused by oxidative stress triggered by elevated concentrations of reactive oxygen species (ROS) in cells. Therefore, the development of suitable probes for monitoring such processes is of… read more here.

Keywords: sulfoxide reductase; enantioselective methionine; activity; redox sensors ... See more keywords
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Methionine Sulfoxide Reductase B1 Regulates Hepatocellular Carcinoma Cell Proliferation and Invasion via the Mitogen-Activated Protein Kinase Pathway and Epithelial-Mesenchymal Transition

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recommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2018/5287971

Abstract: Methionine sulfoxide reductase B1 (MsrB1) is a member of the selenoprotein family, which contributes to the reduction of methionine sulfoxides produced from reactive oxygen species (ROS) by redox processes in energy pathways. However, few studies… read more here.

Keywords: sulfoxide reductase; methionine; proliferation; msrb1 ... See more keywords
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Molecular Expression of Bioactive Recombinant Methionine Sulfoxide Reductase A (MsrA).

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recommendations! Published in 2020 at "Protein and peptide letters"

DOI: 10.2174/0929866527666200625201628

Abstract: BACKGROUND The increase in reactive oxygen species (ROS) production during cryopreservation of semen, leads to oxidation of biomolecules affecting the functionality of spermatozoa. Methionine residues in proteins are highly prone to oxidation and get converted… read more here.

Keywords: sulfoxide reductase; msra; methionine; reductase msra ... See more keywords